Hellenic Electronic Center

 

DESPINA SANOUDOU

Soranou Efesiou 4, Athens 115-27

Work Tel: +30-210-6597055

E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it  

EMPLOYMENT AND EDUCATION

Current position:

2008- Assistant Professor Elect, Department of Pharmacology, Medical School, University of Athens

2007- Assistant Professor, Biomedical Research Foundation of the Academy of Athens, Greece

2003- Affiliated Faculty Member, MSc Program “Molecular Basis of Human Disease”, Medical School, University of Crete, Greece

 

Previous Positions:

2003 – 2006 Instructor, Department of Molecular Biology, Biomedical Research Foundation of the Academy of Athens, Greece

2006 3-month sabbatical, Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, U.S.A.

2005 – 2006 Visiting Scholar, Department of Medicine, Boston University School of Medicine, Boston, U.S.A.

2003 Instructor, Department of Pediatrics, Harvard Medical School, Boston, U.S.A.

2003 Instructor, Department of Medicine, Division of Genetics, Children’s Hospital, Boston, U.S.A.

2000 – 2003 Postdoctoral Research Fellow, Department of Medicine, Division of Genetics, Children’s Hospital, Boston, U.S.A.

2000 – 2003 Postdoctoral Research Fellow, Department of Pediatrics, Harvard Medical School, Boston, U.S.A.

1996 – 1999 Ph.D., Department of Pathology, University of Cambridge, Cambridge, U.K.

1995 Research Assistant, Genetic and Reproductive Toxicology Department, GlaxoSmithKline

1993 – 1996 BSc Molecular Biology, University of Hertfordshire, Hertfordshire, UK

CERTIFICATION

1.  

   1. Board Certified in Clinical Molecular Genetics, American Board of Medical Genetics

Including rotations at Clinical Genetic, Genetic Counseling and Molecular Diagnostic Centers in:

Brigham and Women’s Hospital, Boston, USA

Massachusetts General Hospital, Boston, USA

Children’s Hospital, Boston, USA

Genzyme Inc, Framingham, USA 

TRAINING PROGRAMS

2007 Seminar Series in Bioethics, Hellenic Center for Biomedical Ethics, Athens, Greece

2006 Introduction to Clinical Research. Brigham and Women’s Hospital-Center for Clinical Research, Boston, USA.

2006 Human Subjects Research Training Course, 'Collaborative IRB Training Initiative (CITI). Partners Health Care System / University of Miami, USA.

2005 Seminar Series in Bioethics, Hellenic Center for Biomedical Ethics, Athens, Greece

2003 Advanced Counseling Skills: Integrating Theory into Genetic Counseling Practice. Master’s degree program in Genetic Counseling. Brandeis University, USA

2003 World Muscle Society teaching course on clinical, histological and genetic diagnosis of skeletal muscle diseases. Hodmezovasarhely, Hungary.

2000 – 2002 Clinical Molecular Genetics Course. American Board of Medical Genetics. Harvard University.

2001 Genetics, Development and Reproductive Biology. Harvard Medical School.

2001 Human Subjects Research Training Course. Children’s Hospital Boston / University of Miami.

2001 Biostatistics: Statistics for Medical Research. Brigham and Women's Hospital.

2000 Human Subject Protection Education/Training. Children’s Hospital Boston.

 

MAJOR ADMINISTRATIVE RESPONSIBILITIES

2008 – to date Director of “Advanced Topics in Biotechnology” course for the MSc in Bioinformatics, Department of Informatics, University of Athens, Greece.

2007 – to date Director of “Functional Genomics” course for the MSc in Molecular Medicine, Medical School, University of Athens, Greece.

2003 – to date Design of the Molecular Biology research laboratory, purchase of equipment, recruitment/training/supervision of scientific personnel.

Biomedical Research Foundation of the Academy of Athens.

2003 – to date Organizer and Director of the Athens High School Outreach Program.

Biomedical Research Foundation of the Academy of Athens (hosting >100 students/year).

2000-2003 Establishment, supervision and recruitment/training of personnel of the departmental Microarray Core Facility.

Genomics Program, Children’s Hospital – Harvard Medical School

 

MAJOR COMMITTEE ASSIGNMENTS

2006 – to date MSc course on Informatics Technologies in Medicine and Biology.

Department of Informatics and Technology, University of Athens.

Course Organizing Committee, Head of Advanced Biotechnology section

2006 – to date Young Scientist Forum-Federation of European Biochemical Societies (FEBS) 2008 Organizing Committee

2006 Meeting on Bioinformatics and Medical Informatics.

Foundation for Biomedical Research of the Academy of Athens.

Scientific Committee

2005 – 2006 1^st Molecular Cardiology Course of the Hellenic Cardiological Society.

Organizing Committee, Head

2005 – 2006 Committee for compilation of the Foundation’s Bylaws and Regulations.

Foundation for Biomedical Research of the Academy of Athens

2005 – 2006 Committee for the design and population of the Foundation’s Official Website. Foundation for Biomedical Research of the Academy of Athens.

2004 – 2005 Hellenic Proteomics Society

Elected Board Member

2003 – 2006 Committee for evaluation and selection of the Foundation’s Equipment and Consumables. (Total budget handled: 650,000 euro)

Foundation for Biomedical Research of the Academy of Athens.

 

AWARDS

2008 Panhellenic Biosciences Association Award for contribution to bridging Education and Research and to the education of high-school students and teachers. September 27^th at 3^rd National Conference of the Panhellenic Biosciences Association in Thessaloniki.

2008 Hellenic Cardiological Society 1^st Annual Prize for Excellence in Research

2008 Honorary Award for Scientific Achievements in Molecular Cardiology by the Thirean Society for Sciences and Arts

2008 European Society of Human Genetics National Award

2007 Hellenic Cardiological Society 1^st Annual Prize for Excellence in Research

2007 UNESCO-L’Oreal Award for “Best Young Female Scientist in Greece”

2006 Hellenic Cardiological Society 1^st Annual Prize for Excellence in Research

2000 March of Dimes Birth Defects Foundation Travel Award

1989 – 1993 Five consecutive prizes for academic excellence (Aristeia).

1992, 1993 School Gold Medal winner (Vraveia).

1993 City of Athens award for best final year performance.

1993 City of Athens award for University entrance.  

PROFESSIONAL SOCIETIEs 

• American Society of Human Genetics

• American College of Medical Genetics

• European Society of Human Genetics

• National Society for Genetic Counselors (USA)

• British Institute of Biology

• World Muscle Society

• Hellenic Cardiac Fund for Children (Boston)

• Hellenic Proteomics Society

• Hellenic Society of Medical Genetics

• Panhellenic Union for Biosciences 

RESEARCH SUPPORT

2008-2009 Principal Invesigator, Hellenic Cardiological Society Research Award

“New proteins involved in the development of Heart Failure”

2007 – 2010 Principal Investigator of Genomics sub-project, 6^th Framework Programme-European Union, contract no.: 037277

“Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival”.

2007-2008 Principal Investigator, Hellenic Cardiological Society Research Award

“Characterizing the role of MLP in Heart Failure”

2007 – 2010 Collaborator, 6^th Framework Programme-European Union

“Functional genomics of inborn errors and therapeutic interventions in high density lipoprotein (HDL) metabolism”

2006-2007 Principal Investigator, Hellenic Cardiological Society Research Award

“Evaluation of HAX-1 as a diagnostic marker and therapeutic target for heart failure”

 

2006 – 2008 Co-Investigator, International RTD Collaborations-Greek Ministry of Development/ European Union.

“Models of Ubiquitin-proteasome dysfunction in mice”

 

2006 – 2008 Co-Investigator, Development Programmes for the Periphery, Greek Ministry of Development/ European Union.

“Development of improved cardioprotective gene transfer approaches for cardiomyopathy treatment”

 

2005 – 2008 Co-Investigator, PENED-Greek Ministry of Development/European Union, contract no.: 03 ED 271

“Molecular diagnosis of micrometastatic disease in breast cancer using electronic DNA microarrays”.

 

2006 – 2010 External collaborator, Leducq Foundation: Trans-Atlantic Alliance

“Genetic variants of calcium cycling proteins in heart failure”

 

2006 - 2010 External collaborator, NIH/NHLBI SCCOR grant

“Cardiac Dysfunction and Disease: Genetic and Molecular Signaling in Heart Failure”

 

TEACHING EXPERIENCE

2008 – to date “Advanced Topics in Biotechnology”.

MSc Program, Bioinfromatics, Department of Informatics, University of Athens, Greece.

2007 – to date “Functional Genomics”.

MSc Program, Molecular Medicine, Medical School, University of Athens, Greece.

2006 – to date “Clinical application of microarray technologies”.

MSc Program, Clinical Biochemistry Department, University of Athens, Greece.

2006, 2008 “Animal Models for the study of Heart Disease”,

1^st Molecular Cardiology Course of the Hellenic Cardiological Society. Athens, Greece.

2006, 2008 “Cell and Gene therapy for treating Heart Disease”,

1^st Molecular Cardiology Course of the Hellenic Cardiological Society. Athens, Greece.

2005 – 2006 “The impact of microarray technologies for decoding neuromuscular diseases and Bioethical considerations”.

European Summer Academy on Bioethics, Ludwigshafen, Germany.

2005 – to date “Bioethical considerations in Genetics Research and Application”.

MSc Program, Medical School, University of Crete, Greece.

2005 – to date “Microarray technologies and applications”.

MSc Program, Molecular Medicine, Medical School, University of Athens, Greece.

2005 – to date Organizer and main presenter of the Athens High School Outreach program

2004 – to date “Microarray technologies and applications”.

MSc Program, Chemistry Department, University of Athens, Greece.

2003 – to date “Microarray technologies and applications”.

MSc Program, Medical School, University of Crete, Greece.

March 2003 “Research and the value of Human Genetics”. 2-hour lecture, 2003 New England Junior Science and Humanities Symposium at Harvard Medical School.

April 2002 "DNA microarrays technical aspects and applications". 3-hour seminar,

Medical School, University of Athens, Greece.

2000 – 2003 Training and partial supervision of several postdoctoral fellows, PhD and Master's students, and laboratory technicians in Dr Alan Beggs and Professor Louis Kunkel laboratories. These techniques included extensive work with RNA, use of Microarrays, and use of bio-informatics computer software for data analysis.

1997 – 1999 Teaching of the FISH technique to numerous research scholars in Professor Ferguson-Smith and Dr Nick Coleman laboratories. These techniques included DNA extraction, comparative genomic hybridisation (CGH) and 24-colour fluorescent in situ hybridisation (SKY). I was responsible for setting up the CGH technique in the Department of Pathology (University of Cambridge).

STUDENTS SUPERVISED

PhD Students

2008- to date Aggeliki Tserga

2004 – to date Vassiliki Papalouka “Protein binding partners of MLP”

MSc Students

2007 Eleni Pipi “Characterization of MLP protein-protein interactions”

2005 Katerina Dima “Screening DCM patients for HAX1 mutations”

2002 Nimgaonkar Ashish “Comparison of different microarray generations

Undergraduate students

2008-2009 Ioannia Kyriakides “New protocols for RNA extraction from FFPE tissues”

2007 Zoi Galata “Screening DCM patients for mutations in the HRC gene”

2004-2007 Maria Oikonomaki “Protein binding partners of MyBPC-1 and -2”

2006 Orestis Lyros “Screening DCM patients for mutations in calcium cycling genes”

2005-2006 Konstantinos Solomos “Protein binding partners of MLP”

2005-2006 Danai Papaioannou “Protein binding partners of MLP”

2005 Elpida Tsika “Yeast two-hybrid analysis of HAX-1”

INVITED LECTURES

1. “Mutation in calcium homeostasis related genes and Heart Failure”, 9^th Panhellenic Congress in Heart Failure, Athens, Greece.

2. “Revolutionary approaches in Biological research and Molecular diagnostics”, Science Education Day for the Public, organized by the Mayor of Chalkida and the Panhellenic Biologist Union, Chalkida, Greecde.

3. “Microarrays in the diagnosis, prognosis and therapy of Cancer”, Annual Meeting of the Panhellenic Oncology Society, Metsovo, Greece.

4. “Gene expression profiling of kainate treated mouse hippocampi” VALAPODYN mid-term Meeting, Jerusalem, Israel

5. “Knowledge dissemination activities of the VALAPODYN European Network” VALAPODYN mid-term Meeting, Jerusalem, Israel

6. “The multiple roles of Bioinformatics in Genome Analysis” Athens University of Business and Economics, Athens, Greece

7. “Genetics in the 21^st Centruty – The transition to Personalized Medicine” Meeting of the Thirean Society for Sciences and Arts, Santorini, Greece

8. “Analysis of a “humanized” phospholamban mouse model reveals new pathways linking Ca2+ cycling and cardiac electrophysiology” XXVIII European Section Meeting of the International Society for Heart Research, Athens, Greece

9. “Pharmacogenomics of kainate treated mouse hippocampi” VALAPODYN 24 month Meeting, Wolfenbuttel, Germany

10. “Knowledge dissemination activities of the VALAPODYN European Network” VALAPODYN 24 month Meeting, Wolfenbuttel, Germany

11. “Clinical applications of microarrays”. 7^th Symposium on New Molecules in Cancer Therapeutics, Greek Oncology Research Network, Athens, Greece.

12. “Microarrays”. 2^nd Conference on Oncology in primary healthcare, Athens, Greece.

13. “Genetics of cardiomyopathies”. Developments 2008 and Future Prospects 2009 in Cardiology – International Cardiology Conference, Caravel, Athens, Greece.

14. “The technology of microarrays and their applications in combating breast cancer”. 6^th Continuing Education Seminar on Breast Cancer – From Gene to Therapy, Thessaloniki, Greece.

15. “Pharmacogenomics in treating human disease”. Continuing Education Seminars of the MSc Program “Basic Medical Sciences”, Medical School, University of Patras, Greece.

 

1. “Mutation screening, gene expression profiling and protein-protein interactions in the study of DCM”, MaxPlanck Institute of Biophysics, Frankfurt, Germany.

2. “Evaluating the function of test drug-compounds on the PLN-SERCA interaction”, University of Manchester, Manchester, UK.

3. “Understanding the molecular pathophysiology of cardiac and skeletal muscle”, Seminar Series, Biomedical Research Foundation, Academy of Athens, Athens, Greece.

4. “Genomics and Knowledge Dissemination as part of the VALAPODYN European network”, Athens, Greece.

5. “Being a Researcher”, Greek-German Agogi High-school, Palini, Greece.

6. “Research avenues in Molecular Cardiology”, Attiko Hospital, Athens, Greece.

7. “Deciphering the pathogenetic mechanisms in Nemaline Myopathy”, Annual Conference of the Greek Society for Biological Sciences, Kavala, Greece.

8. “Array lessons from the heart”, Leducq Foundation International Consortium Meeting, Santorini, Greece.

9. “Mutations in Ca2+ homeostasis genes in Heart Failure”, Leducq Foundation International Consortium Meeting, Santorini, Greece.

10. “Understanding the molecular pathophysiology of cardiac and skeletal muscle”, Seminar Series, Department of Chemistry, University of Athens.

11. “Microarrays in Basic and Clinical research”. Agilent Technologies sponsored Meeting on Novel Technologies. Biomedical Research Foundation, Academy of Athens, Greece.

12. “Understanding the molecular pathophysiology of cardiac and skeletal muscle”, Invited Lecture, Annual Retreat MSc “Molecular Basis of Human Disease”, Heraklion, Greece.

13. “Progress on the Genomics Component of the VALAPODYN European network”, Liege, Belgium.

14. “Microarray applications in Molecular Cardiology”, Leducq Foundation International Consortium Meeting, New York, USA.

15. “New polymorphisms and Dilated Cardiomyopathy”, Leducq Foundation International Consortium Meeting, New York, USA.

16. “A dominant negative form of the transcription factor c-Jun affects genes that have opposing effects on lipid homeostasis in mice”, Hellenic Atherosclerosis Society, Athens, Greece.

17. “Characterization of key molecular players in skeletal and cardiac muscle disease”, Invited Lecture, Bi-annual Retreat Biomedical Research Foundation of the Academy of Athens, Kamena Vourla, Greece.

18. “PLN mutations and dilated cardiomyopathy”, Developments 2007 and Future Prospects 2008 in Cardiology – International Cardiology Conference, Caravel, Athens, Greece.

19. Closing Speech at 2007 – UNESCO award ceremony for the “Best Young Female Scientist in Greece”.

1. “Addressing technical challenges in array CGH”. Department of Pathology, Brigham and Women’s Hospital, Boston, USA

2. “Microarrays: technology, applications, future prospects”. Seminar Series for Highschool Teachers “Cutting edge technologies in Biosciences”. Pasteur Institute, Athens, Greece.

3. “The microarray technology and its use in deciphering atherosclerosis”. 10^th Annual conference of the Hellenic Society of Lipidiology and Atherosclerosis, Athens, Greece.

4. “Microarrays in decoding muscle disease”. Department of Biological Applications and Technologies, University of Ioannina, Greece.

5. “Research in Greece”, Thirean Society of Sciences and Arts, Athens, Greece.

6. “Microarrays in the diagnosis, prognosis and therapy of muscle disease”. 26th European Workshop for Rheumatology Research. Hersonissos, Crete, Greece

2005

1. “Diaphragm: a skeletal muscle unlike all others”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

2. “The use of microarrays in research, diagnosis and prognosis of cardiomyopathies”. Conference on Cardiology Genetics, Agia Olga, Athens, Greece.

3. “The impact of microarray technologies for decoding neuromuscular diseases and Bioethical considerations”. European Summer Academy on Bioethics, Ludwigshafen, Germany.

4. “Diaphragm: a skeletal muscle unlike all others”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

5. “The molecular signature of diaphragm”. 31st Panhellenic Medical Conference, Athens, Greece.

 

1. “Microarray applications in diagnosis”. 3rd Annual Meeting of the Biologists Union in Greece.

2. “Emerging pharmaceutical applications of microarrays”. 1st International Greek Biotechnology Forum. Athens, Greece.

3. “Bringing microarrays into school classrooms”. Annual Meeting of the Panhellenic Biologists Union.

4. “The study of gene expression in improved prognosis of neuromuscular disorders”. 30th Panhellenic Medical Conference, Athens, Greece.

2003

1. “The transcriptome of TPM3 nemaline myopathy mouse model”. ENMC on Nemaline Myopathy. Szeged, Hungary.

2. “Deciphering the pathophysiology of neuromuscular disease: starting with Nemaline myopahty”. Institute of Technology, University of Crete, Greece.

2002

1. “Pathways affected in Nemaline Myopathy”. Division Chiefs Annual Meeting, Children’s Hospital, Harvard Medical School.

2. “Development of microarrays and applications in congenital myopathies”. Whitaker Cardiovascular Institute, Boston University School of Medicine.

3. "Unusual cases of Cystic Fibrosis". Harvard Institute of Medicine, Boston, USA.

4. "The use of Microarrays in Research and Diagnostics". Genzyme Inc, Framingham, USA.

5. "Norrie Disease under new light". Speech in honor of Francis Collins, Harvard Medical School, Boston, USA.

6. "Gene Expression studies in Nemaline Myopathy". Childrens Hospital, Boston, USA.

7. "Pathways affected in Nemaline Myopathy". International Congress of Neuromuscular Disorders, Vancouver, Canada.

 

1. "Clinical and genetic heterogeneity in Nemaline Myopathy". Harvard Institute of Medicine, Boston, USA.

2. "Microarrays for the study of etiologic, diagnostic and therapeutic targets in ophthalmological disorders". Ophthalmologic Genetic Disorders Meeting, Athens, Greece.

 

1. “Gene therapy in the treatment of myocardial ischaemia”. 22nd Hellenic Congress of Surgery. Athens, Greece.

2. "Large scale gene analysis of expression in congenital myopathies". Children’s Hospital, Boston, USA.

3. “Genetics in the 21st century: Achievements and Promises”. Belloneio Convention Centre. Santorini, Greece.

4. “Gene therapy in the treatment of myocardial ischaemia”. 22nd Hellenic Congress of Surgery. Athens, Greece.

5. "Large scale gene analysis of expression in congenital myopathies". Children’s Hospital, Boston, USA.

PUBLICATIONS

Original Articles

1. Griffin DK, Sanoudou D, Adamski E, McGiffert C, O’Brien P, Wienberg J, Ferguson-Smith MA. 1998. "Chromosome specific comparative genome hybridisation for determining the origin of intrachromosomal duplications". Journal of Medical Genetics, 35 (1); pp. 37-41.

Impact Factor: 4.112 Citations: 16

 

1. Goike HM, Asplund AC, Pettersson EH, Liu L, Sanoudou D, Collins VP. “Acquired rearrangement of an amplified epidermal growth factor receptor (EGFR) gene in a human glioblastoma xenograft”. Journal of Neuropathology and Experimental Neurology, 58 (7); pp. 697-701.

Impact Factor: 5.037 Citations: 9

 

1. Ding X, Sanoudou D, Yang F, Chen H. 1999. "Determination of trisomy 9p by molecular cytogenetic technology". Chinese Journal of Medical Genetics, 16 (6); pp.383-385.

 

1. Sanoudou D, Tingby O, Ferguson-Smith MA, CollinsVP, Coleman N. 2000."Analysis of pilocytic astrocytoma by comparative genomic hybridization". British Journal of Cancer, 82 (6); pp. 1218-1222.

Impact Factor: 3.742 Citations: 26

 

1. Li YC, Lee C, Sanoudou D, Hsu TH, Li SY, Lin CC. 2000. “Interstitial colocalization of two cervid satellites DNAs involved in the genesis of the indian muntjac karyotype”. Chromosome Research, 8 (5); pp. 363-373.

Impact Factor: 2.346 Citations: 14

 

1. Greenberg SA, Sanoudou D, Haslett JN, Kohane IS, Beggs AH, Kunkel LM, Amato AA. 2002. "Molecular Classification of the Inflammatory Myopathies". Neurology, 59 (8); pp. 1170-1182.

Impact Factor: 5.973 Citations: 35

 

1. Ryan MM, Ilkovski B, Strickland CD, Schnell C, Sanoudou D, Midgett C, Houston R, Muirhead D, Dennett X, Shield LK, deGirolami U, Iannaccone ST, Laing NG, North KN, Beggs AH. 2002. "Clinical course correlates poorly with muscle pathology in Nemaline Myopathy".Neurology, 60 (4); pp. 665-673.

Impact Factor: 5.973 Citations: 17

 

1. Haslett JN, Sanoudou D, Kho A, Bennett RR, Greenberg SA, Kohane IS, Beggs AH, Kunkel LM. 2002.”Comparison of gene expression between Duchenne muscular dystrophy and normal skeletal muscle”. PNAS, 99 (23); pp. 15000-15005.

Impact Factor: 10.700 Citations: 60

 

1. Sanoudou D, Haslett JN, Kho A, Guo O, Gazda H, Greenberg SA, Lidov HGW, Kohane IS, Kunkel LM, Beggs AH. 2002. “Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopahty muscle”. PNAS, 100 (8); pp. 4666-4671.

Impact Factor: 10.700 Citations: 15

 

1. Haslett JN, Sanoudou D, Kho A, Han M, Bennett RR, Kohane IS, Beggs AH, Kunkel LM. 2002. “Gene expression profiling of Duchenne muscular dystrophy and unaffected skeletal muscle biopsies”. Neurogenetics, 4(4):163-71.

Impact Factor: 3.361 Citations: 6

 

1. Sanoudou D*, Nimgaonkar A*, Butte AJ, Haslett JN, Kunkel LM, Beggs AH, Kohane IS. 2003. "Reproducibility of gene expression across generations of Affymetrix microarrays". BMC Bioinformatics, 4 (1):27. *equal contribution

Impact Factor: 5.423 Citations: 22

 

1. Sanoudou D*, Mahler-Araujo MB*, Tingby O, Liu L, Ferguson-Smith MA, Coleman N, Ichimura K, Collins VP. 2003. "Structural genomic abnormalities of chromosome 9 and 18 in myxopapillary ependymomas". J Neuropathol Exp Neurol., 62(9):927-35. *equal contribution

Impact Factor: 5.037 Citations: 2

 

1. Sanoudou D, Frieden LA, Haslett JN, Kho AT, Greenberg SA, Kohane IS, Kunkel LM, Beggs AH. 2004. “Molecular classification of nemaline myopathies:”non-typing” specimens exhibit unique patterns of gene expression”. Neurobiology of disease, 15(3):590-600.

Impact Factor: 5.153 Citations: 6

 

1. Sanoudou D, Kang P, Haslett JN, Han M, Kunkel LM, Beggs AH. 2004. “The transcriptional profile of post mortem skeletal muscle”. Physiological Genomics, 16(5):222-8.

Impact Factor: 4.667 Citations: 4

 

1. Tomczak K, Marinescu V, Ramoni M, Sanoudou D, Montenaro F, Kunkel LM, Kohane IS, Beggs AH. 2004. “Molecular pathways activated during myoblast differentiation in vitro”. FASEB J., 18(2):403-5.

Impact Factor: 7.252 Citations: 31

 

1. Liadaki K, Kho AT, Sanoudou D, Schienda J, Flint A, Beggs AH, Kohane IS, Kunkel LM. 2005. “Side population cells isolated from different tissues share transcriptome signatures and express tissue-specific markers”. Experimental Cell Research, 303(2):360-374.

Impact Factor: 4.007 Citations: 1

 

1. Greenberg SA, Bradshaw E, Park P, Burleson T, Sanoudou D, Slaney M, Due B, Ericsson M, Tawil R, Barohn RJ, Saperstein DS, Briemberg HR, O’Connor K, Bregolli L, Pinkus GS, Pinkus JL, Amato AA. 2005. “Interferon- Mediated Innate Immune Mechanisms in Dermatomyositis”. Annals of Neurology 57(5):664-78.

Impact Factor: 8.097 Citations: 9

 

1. Kang P, Kho AT, Sanoudou D, Haslett JN, Dow C, Han M, Blasko J, Lidov HGW, Beggs AH, Kunkel LM. 2004. “Variations in gene expression among different types of human skeletal muscle”. Muscle Nerve 32(4):483-91.

Impact Factor: 2.432 Citations:

 

1. Haslett JN, Kang PB, Han M, Kho AT, Sanoudou D, Volinski JM, Beggs AH, Kohane IS, Kunkel LM. 2005. “The influence of muscle type and dystrophin deficiency on murine expression profiles”. Mamm Genome 16(10):739-48.

Impact Factor: 2.658 Citations:

 

1. Barnés CM, Huang S, Kaipainen A, Sanoudou D, Chen EJ, Guo Y, Eichler G, Chung HY, Yu Y, Bischoff J, Ingber DE, Mulliken JB, Beggs AH, Folkman J, Fishman SJ. 2005. “Evidence by Molecular Profiling for a Placental Origin of Hemangioma”. Proc Natl Acad Sci U S A. 102(52):19097-19102.

Impact Factor: 10.700 Citations:

 

1. Gazda HT, Kho AT, Sanoudou D, Zaucha JM, Kohane IS, Sieff CA, Beggs AH. 2006. Defective Ribosomal Protein Gene Expression Alters Transcription, Translation, Apoptosis And Oncogenic Pathways In Diamond-Blackfan Anemia. Stem Cells, 24(9):2034-2044.

Impact Factor: 5.500 Citations:

 

1. Sanoudou D, Corbett MA, Han M, Ghoddusi M, Nguyen MT, Vlahovich N, Hardeman EC, Beggs AH. 2006. “Evidence for a skeletal muscle repair process present in a mouse model of nemaline myopathy”. Human Molecular Genetics, 15(17):2603-12.

Impact Factor: 7.764

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kranias EG, Kontrogianni-Konstantopoulos A. 2006. “Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function”. Journal of Molecular Biology, 367(1):65-79.

Impact Factor: 5.229

 

1. Drosatos K, Sanoudou D, Kypreos EK, Kardassis D, Zannis VI. 2007. “A dominant negative form of the transcription factor c-Jun affects genes that have opposing effects on lipid homeostasis in mice”. Journal of Biological Chemistry. In Press.

Impact Factor: 5.865

 

1. Arvanitis DA, Vafiadaki E, Mitton B, Gregory KN, Kranias EG*, Sanoudou D*. 2007. “Histidine-rich calcium binding protein a novel binding partner of SERCA2 in human heart”. American Journal of Physiology Heart and Circulatory Physiology, 293(3):H1581-9. *equal contribution

Impact Factor: 3.568

 

1. Garbis S, Tyritzis S, Roumeliotis T, Zerefos P, Giannopoulou EG, Vlahou A, Kossida S, Diaz J, Vourekas S, Tamvakopoulos C, Pavlakis K, Sanoudou D, Constantinides C. 2008. “Quantitative proteomic determination of potential cancer biomarkers in prostate tissue derived from a human pilot clinical study”. Journal of Proteome Research, 7(8):3146-58.

Impact Factor: 5.151

 

1. Arvanitis DA, Sanoudou D, Vafiadaki E, Kolokathis F, Kontrogianni-Konstantopoulos A, Kremastinos D, Kranias EG. 2008. “Role of histidine-rich calcium binding protein genetic variants in dilated cardiomyopathy patients”. European Heart Journal, (20):2514-25.

Impact Factor: 7.286

 

1. Vafiadaki E, Arvanitis DA, Pagakis SN, Papalouka V, Sanoudou D, Kontrogianni-Konstantopoulos A, Kranias EG. 2008. “The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival”. Molecular Biology of the Cell.

Impact Factor: 6.500

 

1. Psarras S, Sanoudou D*, Mavroidis M*, Xanthou G*, Panoutsakopoulou V, Capetanaki Y. 2008. “Severe activation of inflammatory pathways contributes to desmin null dilated cardiomyopathy”. In submission. *equal contribution

 

 

Reviews and Chapters

 

1. Sanoudou D, Beggs A. 2001. “Clinical and genetic heterogeneity in Nemaline Myopathy a disease of sarcomeric thin filaments”. Trends in Molecular Medicine (formerly Molecular Medicine Today), 7 (8); pp. 362-368.

Impact Factor: 7.497 Citations: 24

 

1. Sanoudou D. 2001. “Genetic advances and their implications in the 21^st century”. Research Institute for European and American Studies (RIEAS), 82 (March).

 

1. Sanoudou D, Vafiadaki E, Arvanitis D, Kranias EG, Kontrogianni-Konstantopoulos A. 2005. “Array lessons from the heart: focus on the genome and transcriptome of cardiomyopathies”. Physiological Genomics 21(2):131-43.

Impact Factor: 4.667 Citations:

 

1. Sanoudou D, Mantzoros CS. Genetics of diabetes and obesity. In: Mantzoros C (editor). Obesity and Diabetes. Humana Press, Inc, Totowa, NJ 2006;39-68.

 

1. Sanoudou D, Mantzoros CS. Genetics of diabetes and obesity. In: Mantzoros C (editor). Obesity and Diabetes. 2^nd Edition, IADaskalopoulos Foundation, 2006;39-68.

 

1. Sanoudou D. “Animal Models in Heart Failure”. Continuing education in Molecular Cardiology Text Book, 2006. pp. 45-58.

 

1. Sanoudou D. “Cell and Gene Therapy in Heart Failure”. Continuing education in Molecular Cardiology Text Book, 2006. pp. 59-68.

 

1. Vafiadaki E, Mantzoros CS, Sanoudou D. Genes and gene-environment interactions in the pathogenesis of obesity and the metabolic syndrome, in Mantzoros CS (Editor), Nutrition and Metabolism, IA Daskalopoulos Foundation, 2007: 11-48.

 

1. Vafiadaki E, Mantzoros CS, Sanoudou D. Genes and gene-environment interactions in the pathogenesis of obesity and the metabolic syndrome, in Mantzoros CS (Editor), Nutrition and Metabolism, 2^nd Edition, IA Daskalopoulos Foundation, 2008:11-48.

 

1. Vafiadaki E, Mantzoros CS, Sanoudou D. Genes and gene-environment interactions in the pathogenesis of obesity and the metabolic syndrome, in Mantzoros CS (Editor), Nutrition and Metabolism, Humana Press, Inc, Totowa, NJ 2008. In press.

 

1. Sanoudou D. “Animal Models in Heart Failure”. Continuing education in Molecular Cardiology Text Book, 2008.

 

1. Sanoudou D. “Cell and Gene Therapy in Heart Failure”. Continuing education in Molecular Cardiology Text Book, 2008.

 

1. Vafiadaki E, Papalouka V, Arvanitis DA, Kranias EG, Sanoudou D. 2008. “The role of SERCA2a/PLN complex, Ca²⁺ homeostasis and anti-apoptotic proteins in determining cell fate”. Pflügers Archiv European Journal of Physiology. In press

Impact Factor: 4.807

 

1. Tserga A, Papalouka V, Sanoudou D. 2008. Principles of Molecular Biology and Genetics in Cardiology”. Cardiology Textbook by Professor Kremastinos. Paschalidis editions. In press.

 

1. Papalouka V, Kranias EG, Sanoudou D. 2008. “Molecular Biology and Genetics Techniques in Cardiology”. Cardiology Textbook by Professor Kremastinos. Paschalidis editions. In press.

 

1. Arvanitis DA, Vafiadaki E, Gregory KN, Sanoudou D, Kranias EG. 2008. “The histidine-rich calcium binding protein in regulation of sarcoplasmic reticulum calcium uptake and release”. Current Cardiology Reviews. In submission.

 

 

 

Educational Material

Sanoudou D. 2005. Course Syllabus for Athens High School Outreach Program. Biomedical Research Foundation of the Academy of Athens.

 

 

Thesis

Sanoudou D. 1999. PhD Thesis. “Chromosomal Abnormalities in Primary Neoplasms of the Central Nervous System”.University of Cambridge

 

 

Non-print Material

Roux,A.-F, Gasca,S, Bagheri-Fam,S, Saridaki,A, Sanoudou,D, Ferraz,C, Demaille,J, Ferguson-Smith,M, Scherer,G. 2000. “Cloning, mapping and characterization of PCNXL1, a member of a new family of vertebrate homologs of the Drosophila neurogenic gene pecanex”. EMBL / GenBank / DDBJ databases.

 

 

Patents

“The protein HAX-1 binds phospholamban, the primary regulator of cardiac function”. Greek Patent Office.

 

 

Abstracts

1. Sanoudou D, Chen H, Yang F, O'Brien P, Willat LR, Nash RW, Ferguson-Smith MA. 1997. "Interpretation of complex chromosome rearrangements by chromosome sorting and painting". Cytogenetics and Cell Genetics, 77 (1-2); p 63.

 

1. Griffin D., Sanoudou D, Adamski E, McGiffert C, O’Brien P, Wienberg J, Ferguson-Smith MA. 1997. "Chromosome specific comparative genomic hybridisation for determining the origin of intrachromosomal duplications". Cytogenetics and Cell Genetics, 77 (1-2); p 27.

 

1. Ferguson-Smith MA, Sanoudou D, O'Brien P, Schinzel A. 1997. "Use of reverse painting to detect a deletion in an apparently balanced de novo translocation". Cytogenetics and Cell Genetics, 77 (1-2).

 

1. Grant JW, Sanoudou D, Collins VP, Ferguson-Smith MA, Coleman N. 1998. "Comparative genomic hybridisation in gliosarcomas". Journal of Pathology, 186 (SS); pA3.

 

1. Sanoudou D, Collins VP, Tingby O, Coleman N, Ferguson-Smith MA. 1998. "Investigation of cytogenetic abnormalities in pilocytic astrocytoma". American Journal of Human Genetics, 63 (supl); pA84.

 

1. Ferguson-Smith MA, Sanoudou D, Lee C. 1998. "Microdeletions of DMT1 at 9p24.3 is the commonest cause of 46,XY females". American Journal of Human Genetics, 63 (supl); pA162.

 

1. Grant JW, Sanoudou D, Collins VP, Ferguson-Smith MA, Coleman N. 1998. "Comparative genomic hybridisation in gliosarcomas". Swiss Neuropathological Society Annual Meeting. Geneva, Switzerland. Oral presentation. Journal of Pathology 186: 3A-3A Suppl. S

 

1. Roberts I, Morley-Jacob C, Sanoudou D, Coleman N. 1998. "24 colour FISH and CGH analysis of paediatric neoplasms". UK Children's Cancer Study Group, Basic and Applied Children's Cancer Research Meeting. Newcastle, England. Oral presentation.

 

1. Sanoudou D, Tingby O, Collins VP, Coleman N, Ferguson-Smith MA. 1999. "Consistent genetic abnormalities in myxopapillary ependymomas". Journal of Pathology, (SS). In press.

 

1. Roberts I, Morley-Jacob C, Pett M, Sanoudou D, Nacheva E, Coleman N. 1999. "Novel chromosomal translocations in pediatric sarcomas demonstrated by 24colour FISH". Journal of Pathology, (SS).

 

1. Sanoudou D, Ichimura K, Ferguson-Smith MA, Collins VP, Coleman N. 1999. “Characteristic genetic abnormalities in ependymal tumours of different malignancy grades. American Journal of Human Genetics. 65 (supl); pA320.

 

1. Coleman N, Sanoudou D, Tingby O, Ferguson-Smith MA, Collins VP. 1999. “Identification of consistent aberrations in myxopapillary ependymoma tumours”. American Journal of Human Genetics. 65 (supl); pA122.

 

1. Haslett J, Sanoudou D, Lidov H, Kohane I, Beggs A, Kunkel L. 2000. “The use of microarrays in the analysis of human skeletal muscle”. American Journal of Human Genetics. 67, (supl 2); pA192.

 

1. Sanoudou D, Huang H, Beggs A, Coleman N, Kohane IS, Collins VP. 2001. "Bioinformatics in the genetic characterization of ependymal tumors". American College of Medical Genetics. Miami, USA.

 

1. Sanoudou D, Haslett J, Greenberg SA, Corbett M, Hardeman E, Iannaccone S, Kohane IS, Kunkel L, Beggs AH. 2001. "Gene Expression profiles in Nemaline Myopathy". World Muscle Society. Utah, USA.

 

1. Greenberg SA, Sanoudou D, Haslett J, Kohane IS, Kunkel L, Beggs AH, Amato AA. 2001. "Molecular Classification of Inflammatory and Other Myopathies". American Neurological Association 126th Meeting. Chicago, USA.

 

1. Sanoudou D, Haslett JN, Greenberg SA, Lidov HGW, Kohane IS, Kunkel LM, Beggs AH. 2001."Gene expression in nemaline myopathy skeletal muscle". American Society of Human Genetics. San Diego, USA.

 

1. Haslett JN, Sanoudou D, Greenberg SA, Lidov HGW, Kohane IS, Beggs AH, Kunkel LM. 2001. "Gene expression analysis of muscle of Duchenne muscular dystrophy patients". American Society of Human Genetics. San Diego, USA.

 

1. Nimgaonkar A, Sanoudou D, Butte A, Haslett JN, Kunkel LM, Beggs AH, Kohane IS. 2001. "Reproducibility and selection of probe sets across generations of microarrays". American Society of Human Genetics. San Diego, USA.

 

1. Haslett JN, Sanoudou D, Kho A, Han M, Beggs AH, Kohane IS, Kunkel LM. 2002."Gene expression analysis of dystrophic skeletal muscle". International Congress of Neuromuscular Disorders, Vancouver, Canada.

 

1. Sanoudou D, Haslett JN, Kho AT, Greenberg SA, Kohane IS, Kunkel LM, Beggs AH. 2002. “Pathways affected in nemaline myopathy”. J NEUROL SCI 199: S121-S121 72 Suppl. 1. International Congress of Neuromuscular Disorders, Vancouver, Canada.

 

1. Tomczak K, Sanoudou D, Han M, Kohane IS, Beggs AH. 2002."Gene expression analysis in differentiating C2C12 cells". J NEUROL SCI 199: P476 Suppl. 1. International Congress of Neuromuscular Disorders, Vancouver, Canada.

 

1. Mahler-Araujo MB, Sanoudou D, Tingby O, Liu L, Ferguson-Smith MA, Coleman N, Ichimura K, Collins VP. 2002. "Genetic abnormalities in Myxopapillary ependymomas". 7th European Congress of Neuropathology, Helsinki, Finland.

 

1. Barnes C, Kaipainen A, Sanoudou D, Kaviani A, Fuchs J, Kim HB, Mulliken J, Fauza D, Beggs AH, Fishman S, Folkman J. 2002. "The Role of Placenta in the Origin of Hemangiomas". Society for Women's Health Research, Third annual conference on Sex and Gene Expression (SAGE), San Jose, California.

 

1. Tomczak K, Ramoni M, Sanoudou D, Han M, Kho A, Kohane IS, Beggs AH. 2002."Cluster analysis of gene expression dynamics in differentiating C2C12 myoblasts". AM J HUM GENET 71 (4): 815 Suppl. S. American Society of Human Genetics. Baltimore, USA.

 

1. Agrawal PB, Sanoudou D, Burleson TI, Beggs AH. 2003. “Multiminicore disease: Clinical, Pathological, Genetic and Microarray analysis”. PEDIATR RES 53 (4): 1489 Part 2 Suppl. S. Annual Pediatric Academic Societies' Meeting, Seattle, Washington, USA.

 

1. Agrawal PB, Sanoudou D, Burleson TI, Beggs AH. 2003. “Gene expression patterns of biopsies from multiminicore disease and its comparison with normal skeletal muscle”. J INVEST MED 51: S362-S362 Suppl. 2Clinical Research, Baltimore, USA.

 

1. Mahler-Araujo MB, Sanoudou D, Tingby O, Liu L, Ferguson-Smith MA, Coleman N, Ichimura K, Collins VP. 2003. ”Structural and genomic abnormalities of chromosomes 9 and 18 in myxopapillary ependymomas”. 19th congress of the European Society of Pathology. Ljubljana, Slovenia.

 

1. Kang PB , Haslett JN, Sanoudou D, Kunkel LM. 2003.”An anatomical map of gene expression across human and murine skeletal muscles”. NEUROMUSCULAR DISORD 13 (7-8): 626-626. World Muscle Society. Szeged, Hungary.

 

1. Sanoudou D, Frieden L, Haslett JN, Kho AT, Greenberg SA, Kohane IS, Kunkel LM, Beggs AH. 2003. “Gene expression profiles in nemaline myopathy sub-groups”. NEUROMUSCULAR DISORD 13 (7-8): 618-619. World Muscle Society. Szeged, Hungary.

 

1. Sanoudou D, Corbett MA, Haslett JN, Han M, Kunkel LM, Hardeman EC, Beggs AH. 2003. “Muscle specific transcriptional changes in nemaline myopathy mice”. AM J HUM GENET 73 (5): 1579. American Society of Human Genetics. Los Angeles, USA.

 

1. Liadaki K, Sanoudou D, Schienda J, Kho A, Beggs AH, Kunkel LM. 2003. Transcriptional profiling of adult mouse muscle and bone marrow SP cells. AM J HUM GENET 73 (5): 1566. American Society of Human Genetics. Los Angeles, USA.

 

1. Sanoudou D, Haslett JN, Greenberg SA, Kho AT, Kohane IS, Kunkel LM, Beggs AH. 2003. “Deciphering neuromuscular disease by microarrays”. Hellenic Society for Biochemistry and Molecular Biology. Athens, Greece.

 

1. Gazda H, Sanoudou D, Beggs AH and Sieff CA. 2003. Identification of candidate genes on chromosome 8p Diamond Blackfan anemia using microarrays. BLOOD 102 (11): 1837 Part 1. American Society for Hematology. San Diego, USA.

 

1. Sanoudou D, J.N. Haslett, S.A. Greenberg, A.T. Kho, I.K. Kohane, L.M. Kunkel, A.H. Beggs. 2004. “The study of gene expression in improved prognosis of neuromuscular disorders”. Annual Hellenic Medical Conference, Athens, Greece.

 

1. Gazda H, Sanoudou D, Kho AT, Zaucha JM, Sieff CA, Beggs AH. 2004. “Gene Expression changes in bone marrow cells from Diamond-Blackfan anemia patients”. 5th International Diamond-Blackfan Anemia Consensus Conference, New York, USA.

 

1. Kang PB, Kho AT, Sanoudou D, Haslett JN, Dow C, Han M, Blasko J, Lidov HGW, Beggs AH, Kunkel LM. 2004. “Variations in gene expression among different types of human skeletal muscle”. NEUROMUSCULAR DISORD 14 (7-8): 619. World Muscle Society. Gothenburg, Sweden.

 

1. Sanoudou D, Buj-Bello A, Burleson T, Pierson C, Laporte J, Mandel JL, Beggs AH. 2004. “The transcriptome of X-linked recessive myotubular myopathy (XMTM) muscle”. American Society of Human Genetics. Toronto, Canada.

 

1. Tomczak K, Zerra PE, Buj-Bello A, Pierson CR, Sanoudou D, Laporte J, Mandel JL, Beggs AH. 2005. “siRNA knockdown of myotubularin results in transcriptional but not morphologic changes during myogenic differentiation in C2C12 cells”. Experimental Biology, Annual Meeting. San Diego, USA.

 

1. Gazda H, Sanoudou D, Kho AT, Zaucha JM, Sieff CA, Beggs AH. 2005. “Gene Expression changes in bone marrow cells from Diamond-Blackfan anemia patients”. American Society for Hematology. San Diego, USA. BLOOD 104 (11): 206A-207A 720 Part 1

 

1. Sanoudou D, Buj-Bello A, Pierson C, Tomczak K, Burleson T, Laporte J, Mandel JL, Beggs AH. 2005. “Molecular consequences of MTM1 mutations in X-linked myotubular myopathy muscle”. European Society of Human Genetics Annual Meeting, Prague.

 

1. Sanoudou D, Corbett MA, Arvanitis D, Vafiadaki E, Spiliopoulou C, Hardeman EC, Beggs AH. 2005 “The molecular signature of diaphragm”. 31st Panhellenic Medical Conference, Athens, Greece.

 

1. Gazda H, , Kho AT, Sanoudou D Zaucha JM, Sieff CA, Beggs AH. 2005. “Defective ribosomal protein gene expression alters transcription, translation and oncogenic pathways in Diamond-Blackfan anemia”. American Society for Hematology. BLOOD 106 (11): 990A-990A 3546 Part 1

 

1. Tomczak K, Zerra PE, Buj-Bello A, Pierson CR, Sanoudou D, Laporte J, Mandel JL, Beggs AH. 2005. “Myotubularin siRNA knockdown in C2C12 cells results in upregulation of doublecortin”. 2^nd Internationl Myology Congress, Nantes, France.

 

1. Arvanitis DA, Sanoudou D, Vafiadaki E, Haghighi K, Kolokathis F, Kremastinos D, Kontrogianni-Konstantopoulos , Kranias EG. 2005. “Mutation screening of histidine rich calcium binding protein (HRC) gene in heart failure patients”. International Mutation Detection Conference 2005, Santorini, Greece.

 

1. Arvanitis DA, Vafiadaki E, Sanoudou D, Haghighi K, Kolokathis F, Kremastinos D, Kranias EG, Kontrogianni-Konstantopoulos. 2005. “Mutation analysis of small ankyrin 1(sANK1) gene muscle specific isoform in patients with dilated cardiomyopathy. International Mutation Detection Conference 2005, Santorini, Greece.

 

1. Sanoudou D, Arvanitis DA, Papadodima S, Kotretsos P, Corbett MA, Vafiadaki E, Spiliopoulou C, Hardeman EC, Beggs AH. 2005 “Diaphragm: a skeletal muscle unlike all others”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

 

1. Vafiadaki E, Arvanitis DA, Sanoudou D, Papalouka V, Kranias EG, Kontrogianni-Konstantopoulos A. 2005 ”A molecular investigation of the role of phospholamban in cardiac muscle”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

 

1. Papalouka V, Vafiadaki E, Arvanitis DA, Kontrogianni-Konstantopoulos A, Kranias EG, Sanoudou D. 2005 “Identifying new binding partners of CSRP3 through the yeast two-hybrid system”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

 

1. Arvanitis DA, Sanoudou D, Vafiadaki E, Haghighi K, Kolokathis F, Kremastinos DT, Kontrogianni-Konstantopoulos A, Kranias EG. 2005 “Genetic alterations identified in HRC and sANK1 genes in dilated cardiomyopathy patients”. 57th Annual Meeting of the Hellenic Society of biochemistry and Molecular Biology. Athens, Greece.

 

1. Drosatos K, Kypreos KE, Sanoudou D, Kardassis D, Zannis VI. 2006. “Adenovirus mediated gene transfer of a dominant negative form of the transcriptional factor c-Jun in mice triggers distinct mechanisms with opposing effects on the mouse lipid levels”. 7th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Denver, USA. Arteriosclerosis, thrombosis and vascular biology 26 (5): E66-E66

 

1. Tomczak KK, Pierson C, Zerra, PE, Buj-Bello A, Sanoudou D, Laporte J, Mandel JL, Beggs AH. 2006. “Transcriptional changes associated with myotubularin knockdown in differentiating C2C12 myoblasts”. New Directions in Skeletal Muscle Biology Meeting, Texas, USA.

 

1. Drosatos K, Kypreos KE, Sanoudou D, Kardassis D, Zannis VI. 2006. “Adenovirus mediated gene transfer of a dominant negative form of the transcriptional factor c-Jun in mice triggers distinct mechanisms with opposing effects on the mouse lipid levels”. 10th Annual conference of the Hellenic Society of Lipidiology and Atherosclerosis, Athens, Greece.

 

1. Skarlas L, Tsavachidou D, Sanoudou D, Likothanassis S, Kalofonos H, Weber BL. 2006. “MAPS: MicroArray Processing Software for management, data mining and visualization of gene expression data". International Conference in Computational Methods in Science and Engineering 2006 (ICCMSE 2006). Crete, Greece.

 

1. Tomczak KK, Pierson CR, Zerra PE, Buj-Bello A, Sanoudou D, Laporte J, Mandel JL, Beggs AH. 2007. “siRNA knockdown of myotubularin results in transcriptional up-regulation of doublecortin during myogenic differentiation in C2C12 cells”. American Academy of Neurology Annual Meeting. Boston, MA, USA.

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kontrogianni-Konstantopoulos A, Kranias EG. 2007. “HAX-1 is a new interacting protein of Phospholamban and a novel regulator of calcium homeostasis and cardiac cell survival”. European Society of Human Genetics Annual Meeting, Nice, France.

 

1. Drosatos K, Sanoudou D, Kypreos KE, Kardassis D, Zannis VI. 2007. “A dominant negative form of the transcriptional factor c-Jun affects two lipid metabolism related genes that result in opposite effects on mouse plasma lipid levels”. European Society of Human Genetics Annual Meeting, Nice, France.

 

1. Arvanitis DA, Vafiadaki E, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Kranias EG, Sanoudou D. 2007. “Histidine-Rich Calcium Interacts with SERCA2 in a Ca-dependent manner”. European Society of Human Genetics Annual Meeting, Nice, France.

 

1. Depaulis A, Vafiadaki E, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2007. “VALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival”. European Society of Human Genetics Annual Meeting, Nice, France.

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kontrogianni-Konstantopoulos A, Kranias EG. 2007. “Identification of a Novel Interaction Between HAX-1 and Phospholamban in Cardiac Muscle and its Role in Cell Survival”. European Society of Cardiology Annual Congress.

 

1. Arvanitis DA, Vafiadaki E, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. 2007. “Histidine-Rich Calcium Binding Protein as Novel Mediator Between Sarcoplasmic Reticulum Ca uptake and Release”. European Society of Cardiology Annual Congress.

 

1. Depaulis A, Vafiadaki E, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2007. “VALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival”. International Proteomics Conference - From Discovery to Applications, Crete, Greece.

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kontrogianni-Konstantopoulos A, Kranias EG. 2007. “HAX-1 is a novel interacting protein of Phospholamban in cardiac muscle”. Annual Conference of the Greek Society for Biological Sciences, Kavala, Greece.

 

1. Depaulis A, Vafiadaki E, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2007. “VALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival”. Annual Conference of the Greek Society for Biological Sciences, Kavala, Greece.

 

1. Arvanitis DA, Vafiadaki E, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. 2007. “HRC protein binds to SERCA2”. Annual Conference of the Greek Society for Biological Sciences, Kavala, Greece.

 

1. Depaulis A, Vafiadaki E, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2007. “VALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival”. Proteomics Europe 2007, Amsterdam, Netherlands.

 

1. Arvanitis DA, Kolokathis F, Sanoudou D, Vafiadaki E, Theodorakis GN, Kontrogianni-Konstantopoulos A, Paraskevaidis IA, Adamopoulos S, Dorn G II, Kremastinos D, Kranias EG. 2007. “Ser96Ala Variant of Histidine-Rich Calcium Binding Protein Is Associated With Malignant Ventricular Arrhythmias in Nonischemic Dilated Cardiomyopathy”. 28^th Panhellenic Cardiological Congress, Rhodes, Greece.

 

1. Jackers P, Bertrand V, Vafiadaki E, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, Dumas Milne Edwards JB, Sanoudou D, Depaulis A, De Pauw E. 2007 “Dynamic proteomics of mice hippocampus to study apoptosis”. Proteomics Europe, Amsterdam, Netherlands.

 

1. Arvanitis DA, Zhao W, Vafiadaki E, Haghighi K, Kranias EG, Sanoudou D. 2007. “Alterations in cardiac electrophysiology of the phospholamban knock-out mouse expressing the human ortholog protein”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kranias EG, Kontrogianni-Konstantopoulos A. 2007. “HAX-1 interacts with phospholamban and represents a novel regulator of calcium homeostasis and cell survival in cardiac muscle”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Kranias EG, Sanoudou D. 2007. “A novel role for HRC in cardiomyocyte Ca²⁺ cycling through interaction with SERCA2”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Galata Z, Papalouka V, Oikonomaki M, Arvanitis DA, Kolokathis F, Kremastinos D, Kranias EG, Sanoudou D. 2007. “Searching for cardiac myosin binding protein C sequence variations in dilated cardiomyopathy patients”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Papalouka V, Vafiadaki E, Arvanitis DA, Kontrogianni-Konstantopoulos A, Kranias EG, Sanoudou D. 2007. “MyBP-C3, a novel interacting partner of CSRP3”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Vafiadaki E, Depaulis A, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2007. “A systems biology approach targeting neurological disease from genomics in silico predictive models”. 59th Annual Meeting of the Hellenic Society of Biochemistry and Molecular Biology. Athens, Greece.

 

1. Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kranias EG, Kontrogianni-Konstantopoulos A. 2007. “HAX-1 interacts with phospholamban and represents a novel regulator of calcium homeostasis and cell survival in cardiac muscle”. Leducq Foundation Transatlantic Meeting, New York, USA.

 

1. Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. 2007. “A novel role for HRC in cardiomyocyte Ca²⁺ cycling through interaction with SERCA2”. 2007. Leducq Foundation Transatlantic Meeting, New York, USA.

 

1. Sanoudou D, Kretz C, Beggs AH, Laporte J, Buf-Bello A, Mandel J, Al-Qusairi. 2007. “Molecular mechanisms underlying X-linked myotubular myopathy”. 12rh International Congress of the World Muscle Society, Sicily, Italy.

 

1. Jackers P, Bertrand V, Vafiadaki E, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, Dumas Milne Edwards JB, Sanoudou D, Depaulis A, De Pauw E. 2008. “Dynamic proteomics of mice hippocampus to study apoptosis”. Annual Meeting of the Belgian Society for Mass Spectrometry, Beerse, Belgium.

 

1. Arvanitis DA, Dong M, Zhao W, Vafiadaki E, Kranias EG, Wang H-S, Sanoudou D. 2008. “Analysis of a “humanized” phospholamban mouse model reveals new pathways linking Ca2+ cycling and cardiac electrophysiology”. XXVIII European Section Meeting of the International Society for Heart Research, Athens, Greece

 

1. Arvanitis DA, Sanoudou D, Kolokathis F, Vafiadaki E, Kontrogianni A, Theodorakis G, Paraskevaidis I, Adamopoulos S, Dorn GW II , Kremastinos D, Kranias EG. 2008. “HRC polymorphism associated with life-threatening ventricular arrhythmias in cardiomyopathy patients”. XXVIII European Section Meeting of the International Society for Heart Research, Athens, Greece

 

1. Arvanitis DA, Dong M, Zhao W, Papalouka V, Kranias EG, Wang H-S, Sanoudou D. 2008. “Significant impairments in ion transport and cardiac cytoarchitecture in the “humanized” phospholamban mouse model”. 3^rd International Myology Congress, Marseille, France.

 

1. Al-Qusairi L, Weiss N, Sanoudou D, Berbey C, Messaddeq N, Kretz C, Allard B, Beggs AH, Mandel JL, Jacquemond V, Laporte J, Buj Bello A. 2008. “Defects in excitation-contration coupling in X-linked myotubular myopathy”. 3^rd International Myology Congress, Marseille, France.

 

1. Arvanitis DA, Sanoudou D, Kolokathis F, Vafiadaki E, Kontrogianni A, Theodorakis G, Paraskevaidis I, Adamopoulos S, Dorn GW II , Kremastinos D, Kranias EG. 2008. “A genetic variant of the histidine-rich calcium binding protein cofers susceptibility to arrhythmogenesis and sudden cardiac death in DCM patients”. 3^rd International Myology Congress, Marseille, France.

 

1. Vafiadaki E, Depaulis A, Jackers P, Arvanitis DA, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2008. “Developing predictive dynamic models of complex intracellular networks for neurological disease”. 33^rd Federation of European Biochemical Societies (FEBS) Congress, Athens, Greece.

 

1. Kolokathis F, Arvanitis DA, Sanoudou D, Vafiadaki E, Theodorakis G, Paraskevaidis I, Adamopoulos S, Dorn GW II , Kremastinos D, Kranias EG. 2008. “A Histidine-Rich Calcium binding protein genetic variant is associated with malignant ventricular arrhythmias in patients with dilated cardiomyopathy”. European Society of Cardiology Congress 2008, Munich, Germany.

 

1. Arvanitis DA, Dong M, Zhao W, Papalouka V, Kranias EG, Wang H-S, Sanoudou D. 2008. “Changes in Ca homeostasis lead to electrical and structural remodeling of the heart in the “human PLN” mouse model”. 40^th European Human Genetics Congress, Barcelona, Spain.

 

1. Depaulis A, Vafiadaki E, Jackers P, Kel-Margoulis O, Wingender E, Vujasinovic T, Greenberg D, Soreq H, De Pauw E, Dumas Milne Edwards JB, Sanoudou D. 2008. “VALAPODYN: a new systems biology approach to develop predictive dynamic models of complex intracellular networks for neurological disease”. 9^th International Conference on Systems Biology, Gothenburg, Sweden.

 

1. Vafiadaki E, Arvanitis DA, Pagakis SN, Papalouka V, Sanoudou D, Kontrogianni-Konstantopoulos A, Kranias EG. 2008. “HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival”. Mitochondrial Biology in Cardiovascular Health and Disease. National Institute of Health, Bethesda, USA.

 

1. Vorkas P, Sanoudou D. 2008. “Microarrays in Oncology for improved diagnosis, prognosis and pharmacogenomics”. Seminars in Oncology 2008, Athens, Greece.

 

 

 

Editorial Boards

 

2008- to date Central European Journal of Medicine (Section Editor for Genetics)

 

 

Manuscript Reviewer for

 

• Physiological Genomics (3)

• Annals of Neurology (4)

• Prenatal Diagnosis (1)

• Clinical Genetics (1)

• Neuromuscular Disorders (1)

• Medical Science Monitor (1)

• Journal of Molecular and Cellular Cardiology (1)

• BMC BioMedical Engineering (1)

• Neuropediatrics (1)

• Neuroimmunology (1)

 

 

Grant Reviewer for

 

• 7^th Framework Programme of the European Union